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    It is becoming more widely recognized thattumors can carry specific mutations that impact the choice oftherapy and the overall prognosis. del Castillo FJ, Rodriguez-Ballesteros M, Alvarez A, Hutchin T, Leonardi E, de Oliveira CA,Azaiez H, Brownstein Z, Avenarius MR, Marlin S, Pandya A, Shahin H, Siemering KR, WeilD, Wuyts W, Aguirre LA, Martin Y, Moreno-Pelayo MA, Villamar M, Avraham KB, DahlH-HM, Kanaan M, Nance WE, Petit C, Smith RJH, Van Camp G, Sartorato EL, Murgia A,Moreno F, del Castillo I (2005) A novel deletion involving the connexin-30 gene, del(GJB6-d13s1854), found in trans with mutations in the GJB2 gene (connexin-26) in subjects withDFNB1 non-syndromic hearing impairment.

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    This is good news for pharma-ceutical companies and for clinicians who feel inadequate in the face of thetide of despair, misery, and loss brought to them on a daily basis in the privatepractices of medicine and psychology around the modern world.

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    Dose-dependent fetal complications of warfarin in pregnant women with mechanicalheart valves.

    Oneimportant application is to import all of the open literature(e.g., from PubMed) into a knowledge base by parsing allsentences containing a set of predefined objects or terms,which might be chemicals, genes, and diseases as definedby common ontologies.

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